Use DEV as eBUS device [/dev/ttyUSB0]. This can be either: enh:DEVICE or enh:IP:PORT for enhanced device (only adapter v3 and newer), ens:DEVICE for enhanced high speed serial device (only adapter v3 and newer with firmware since 20220731), DEVICE for serial device (normal speed, for all other serial adapters like adapter v2 as well as adapter v3 in non-enhanced mode), or [udp:]IP:PORT for network device.
Source: https://github.com/john30/ebusd/wiki/2.-Run#device-options.