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option

services.pipewire.systemWide

If true, a system-wide PipeWire service and socket is enabled allowing all users in the "pipewire" group to use it simultaneously. If false, then user units are used instead, restricting access to only one user.

Enabling system-wide PipeWire is however not recommended and disabled by default according to https://github.com/PipeWire/pipewire/blob/master/NEWS.