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Description

Cytokine Profiling Analysis Tool.

Provides comprehensive cytokine profiling analysis through quality control using biologically meaningful cutoffs on raw cytokine measurements and by testing for distributional symmetry to recommend appropriate transformations. Offers exploratory data analysis with summary statistics, enhanced boxplots, and barplots, along with univariate and multivariate analytical capabilities for in-depth cytokine profiling such as Principal Component Analysis based on Andrzej Maćkiewicz and Waldemar Ratajczak (1993) <doi:10.1016/0098-3004(93)90090-R>, Sparse Partial Least Squares Discriminant Analysis based on Lê Cao K-A, Boitard S, and Besse P (2011) <doi:10.1186/1471-2105-12-253>, Random Forest based on Breiman, L. (2001) <doi:10.1023/A:1010933404324>, and Extreme Gradient Boosting based on Tianqi Chen and Carlos Guestrin (2016) <doi:10.1145/2939672.2939785>.

CytoProfile CytoProfile website

CRAN Build Status:R-CMD-check ReleaseBuild CRANstatus CRANchecks Downloads Last CommitRelease

Development Build Status:R-CMD-check DevBuild DevVersion Last CommitDev

CodeFactor

The goal of CytoProfile is to conduct quality control using biological meaningful cutoff on raw measured values of cytokines. Specifically, test on distributional symmetry to suggest the adopt of transformation. Conduct exploratory analysis including summary statistics, generate enriched barplots, and boxplots. Further, conduct univariate analysis and multivariate analysis for advance analysis.

Installation

Before installation of the CytoProfile package, make sure to install BiocManager and mixOmics packages using:

## install BiocManager
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") 
## install mixOmics 
BiocManager::install('mixOmics')

You can install the development version of CytoProfile from GitHub with:

# install.packages("devtools")
devtools::install_github("saraswatsh/CytoProfile", ref = "devel")

Install CytoProfile from CRAN with:

install.packages("CytoProfile")

See change log for the latest updates and changes on release build at News and development build at News.

To look at the vignettes included in the package, use:

browseVignettes("CytoProfile")

Vignettes are also available on CytoProfile website to learn how to use the package.

For more details on the released build of the package, please visit the CytoProfile website. For the development version of the package, please visit the Development CytoProfile website.

Metadata

Version

0.2.4

License

Unknown

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