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Description

Modeling, Confidence Intervals and Equivalence of Survival Curves.

We provide a non-parametric and a parametric approach to investigate the equivalence (or non-inferiority) of two survival curves, obtained from two given datasets. The test is based on the creation of confidence intervals at pre-specified time points. For the non-parametric approach, the curves are given by Kaplan-Meier curves and the variance for calculating the confidence intervals is obtained by Greenwood's formula. The parametric approach is based on estimating the underlying distribution, where the user can choose between a Weibull, Exponential, Gaussian, Logistic, Log-normal or a Log-logistic distribution. Estimates for the variance for calculating the confidence bands are obtained by a (parametric) bootstrap approach. For this bootstrap censoring is assumed to be exponentially distributed and estimates are obtained from the datasets under consideration. All details can be found in K.Moellenhoff and A.Tresch: Survival analysis under non-proportional hazards: investigating non-inferiority or equivalence in time-to-event data <arXiv:2009.06699>.
Metadata

Version

0.1.0

License

Unknown

Platforms (75)

    Darwin
    FreeBSD
    Genode
    GHCJS
    Linux
    MMIXware
    NetBSD
    none
    OpenBSD
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    Solaris
    WASI
    Windows
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