Description

'Trial Sequential Analysis' for Error Control and Inference in Sequential Meta-Analyses.

Description

Frequentist sequential meta-analysis based on 'Trial Sequential Analysis' (TSA) in programmed in Java by the Copenhagen Trial Unit (CTU). The primary function is the calculation of group sequential designs for meta-analysis to be used for planning and analysis of both prospective and retrospective sequential meta-analyses to preserve type-I-error control under sequential testing. 'RTSA' includes tools for sample size and trial size calculation for meta-analysis and core meta-analyses methods such as fixed-effect and random-effects models and forest plots. TSA is described in Wetterslev et. al (2008) <doi:10.1016/j.jclinepi.2007.03.013>. The methods for deriving the group sequential designs are based on Jennison and Turnbull (1999, ISBN:9780849303166).

README.md

cran.r-project.org

Overview

RTSA is a R package for sequential meta-analysis using Trial Sequential Analysis (TSA).

Installation

You can install the released version of RTSA from CRAN with:

install.packages("RTSA")

Original software

RTSA is the R version of TSA, originally being developed as a java stand-alone software. The RTSA manual is heavily inspired by the user manual for TSA by Kristian Thorlund, Janus Engstrøm, Jørn Wetterslev, Jesper Brok, Georgina Imberger, and Christian Gluud. To access the original TSA software developed by Copenhagen Trial Unit please go to: https://ctu.dk/tsa/.

Copenhagen Trial Unit Centre for Clinical Intervention Research Department 3344, Rigshospitalet DK-2100 Copenhagen Ø Denmark Tel. +45 3545 7171 Fax +45 3545 7101 E-mail: [email protected].

r-RTSA

Overview

Installation

Original software

Version

License

Status

Source

Homepage

Platforms (75)

Overview

Installation

Original software

Version

License

Status

Source

Homepage

Platforms75 (75)

Platforms (75)