Description
GWAS for Multiple Observations on Related Individuals.
Description
Performs genome-wide association studies (GWAS) on individuals that are both related and have repeated measurements. For each Single Nucleotide Polymorphism (SNP), it computes score statistic based p-values for a linear mixed model including random polygenic effects and a random effect for repeated measurements. The computed p-values can be visualized in a Manhattan plot. For more details see Ronnegard et al. (2016) <doi:10.1111/2041-210X.12535> and for more examples see <https://github.com/larsronn/RepeatABEL_Tutorials>.