Description
Seamless Adaptive Multi-Arm Multi-Stage Enrichment.
Description
Design a Bayesian seamless multi-arm biomarker-enriched phase II/III design with the survival endpoint with allowing sample size re-estimation. James M S Wason, Jean E Abraham, Richard D Baird, Ioannis Gournaris, Anne-Laure Vallier, James D Brenton, Helena M Earl, Adrian P Mander (2015) <doi:10.1038/bjc.2015.278>. Guosheng Yin, Nan Chen, J. Jack Lee (2018) <doi:10.1007/s12561-017-9199-7>. Ying Yuan, Beibei Guo, Mark Munsell, Karen Lu, Amir Jazaeri (2016) <doi:10.1002/sim.6971>.