Description
Feature-Wise Normalization for Microbiome Sequencing Data.
Description
A novel feature-wise normalization method based on a zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and also incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth. Ziyue Wang, Dillon Lloyd, Shanshan Zhao, Alison Motsinger-Reif (2023) <doi:10.1101/2023.10.31.563648>.
README.md
TaxaNorm 
TaxNorm is the R package for a novel feature-wise normalization method for microbiome data based on zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth to better capture the microbiome data nature.
Installation
Current stable release:
install.packages("TaxaNorm")
Build from GitHub:
if (!require(remotes)) install.packages("remotes")
remotes::install_github("wangziyue57/TaxaNorm",
dependencies = TRUE,
build_vignettes = TRUE)