Description
Mutational Signatures from COSMIC (Catalogue of Somatic Mutations in Cancer).
Description
A data package with 2 main package variables: 'signature' and 'etiology'. The 'signature' variable contains the latest mutational signature profiles released on COSMIC <https://cancer.sanger.ac.uk/signatures/> for 3 mutation types: * Single base substitutions in the context of preceding and following bases, * Doublet base substitutions, and * Small insertions and deletions. The 'etiology' variable provides the known or hypothesized causes of signatures. 'cosmicsig' stands for COSMIC signatures. Please run ?'cosmicsig' for more information.
README.md
cosmicsig
Purpose
Mutational signatures data from COSMIC, the Catalogue Of Somatic Mutations In Cancer (https://cancer.sanger.ac.uk/signatures/). There are also some helper functions for handling COSMIC signatures.
Installation
Get the stable version
install.packages("cosmicsig")
Get the development version
Install cosmicsig from the master branch on GitHub:
if (!requireNamespace("remotes", quietly = TRUE)) {
install.packages("remotes")
}
remotes::install_github(repo = "Rozen-Lab/cosmicsig", ref = "master")
Reference manual
https://github.com/Rozen-Lab/cosmicsig/blob/v1.1.1-branch/cosmicsig_1.1.1.pdf.