Description
Piece-Wise Exponential Additive Mixed Modeling Tools for Survival Analysis.
Description
The Piece-wise exponential (Additive Mixed) Model (PAMM; Bender and others (2018) <doi: 10.1177/1471082X17748083>) is a powerful model class for the analysis of survival (or time-to-event) data, based on Generalized Additive (Mixed) Models (GA(M)Ms). It offers intuitive specification and robust estimation of complex survival models with stratified baseline hazards, random effects, time-varying effects, time-dependent covariates and cumulative effects (Bender and others (2019)), as well as support for left-truncated, competing risks and recurrent events data. pammtools provides tidy workflow for survival analysis with PAMMs, including data simulation, transformation and other functions for data preprocessing and model post-processing as well as visualization.
README.md
pammtools: Piece-Wise Exponential Additive Mixed Modeling Tools
Installation
Install from CRAN or GitHub using:
# CRAN
install.packages("pammtools")
Overview
pammtools facilitates the estimation of Piece-wise exponential Additive Mixed Models (PAMMs) for time-to-event data. PAMMs can be represented as generalized additive models and can therefore be estimated using GAM software (e.g. mgcv), which, compared to other packages for survival analysis, often offers more flexibility w.r.t. to the specification of covariate effects (e.g. non-linear, time-varying effects, cumulative effects, etc.).
To get started, see the Articles section.