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Description

Log-Likelihood Functions for 'rxode2'.

Provides the log-likelihoods with gradients from 'stan' (Carpenter et al (2015), <arXiv:1509.07164>) needed for generalized log-likelihood estimation in 'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>). This is split of to reduce computational burden of recompiling 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) which runs the 'nlmixr2' models during estimation.

rxode2ll

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The goal of rxode2ll is to create log-likelihood functions for use in ‘rxode2’ and ‘nlmixr2’

Installation

You can install the development version of rxode2ll from GitHub with:

# install.packages("devtools")
devtools::install_github("nlmixr2/rxode2ll")

Examples

Each of the C++ interface to the stan log-likelihood equations can be used in a stand-alone manner. For example:

llikNorm(seq(-2,2,length.out=10), full=TRUE)

The following log-likelihood distributions are supported:

  • llikNorm()
  • llikPois()
  • llikBinom()
  • llikNbinom()
  • llikNbinomMu()
  • llikBeta()
  • llikT()
  • llikChisq()
  • llikExp()
  • llikF()
  • llikGeom()
  • llikUnif()
  • llikWeibull()
  • llikGamma()
  • llikCauchy()
Metadata

Version

2.0.11

License

Unknown

Platforms (75)

    Darwin
    FreeBSD
    Genode
    GHCJS
    Linux
    MMIXware
    NetBSD
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    OpenBSD
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