Description
Sequential Multiple Assignment Randomized Trial Design.
Description
SMART trial design, as described by He, J., McClish, D., Sabo, R. (2021) <doi:10.1080/19466315.2021.1883472>, includes multiple stages of randomization, where participants are randomized to an initial treatment in the first stage and then subsequently re-randomized between treatments in the following stage.
README.md
The smartDesign
Package
Sequential Multiple Assignment Randomized Trial Design, with two main design options: Single Sequential Treatment (SST) and Dynamic Treatment Regminen (DTR) designs, for which we split into separate calculations and plot methods.
SST
smartSST()
Performs sensitivity and specificity calculations for the SST design given means for G0 and G1, and sample size. User specifies the B level to be applied in the power and the plot functions.
powerSST()
Power for the SST design.
DTR
smartDTR()
Sensitivity and Specificity calculations for given mean and variance vectors for the Dynamic Treatment Regimen (DTR).
powerDTR()
Power to compere two groups of DTR settings. Plot and print methods are available.