Description
Statistical Tools for Immune Correlates Analysis of Vaccine Clinical Trial Data.
Description
Various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled effects (controlled risk and controlled vaccine efficacy), and mediation effects (natural direct effect, natural indirect effect, proportion mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022) <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA (2023) <doi:10.48550/arXiv.2208.06465>.
README.md
vaccine 
Statistical tools for immune correlates analysis of vaccine clinical trial data
Overview
vaccine is an open-source R package containing various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled risk, and controlled vaccine efficacy.
Installation
The latest stable version of vaccine can be installed from CRAN using install.packages():
install.packages("vaccine")
The current development version can be installed using devtools::install_github():
devtools::install_github(repo="Avi-Kenny/vaccine")
Bugs reports and feature requests
To submit a bug report or request a new feature, please submit a new GitHub Issue.